Blog Posts

Clinical Trials in Resource-Limited Settings: Exploring Nepal's Challenges and Solutions

  • January 6, 2024

A Cochrane review of rotavirus vaccines revealed 80–90% protection against severe gastroenteritis in high-resource settings compared to 40–60% efficacy in low-resource settings. Why do interventions that work in industrialized countries face challenges in demonstrating effectiveness in developing nations?

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Designing an ideal Case Report Form (CRF) for Clinical Research

  • January 6, 2024

 

A Case Report Form (CRF), is a printed, optical or electronic document designed to record all of the protocol required information to be reported to the sponsor on each trial subject, as defined by the International Conference on Harmonization Guidelines for Good Clinical Practice.

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Best Practices in Data Management for Clinical Trials: Ensuring Accuracy and Compliance

Data in clinical trials encompass a comprehensive set of information collected during the study, including participant demographics, medical history, treatment outcomes, adverse events, and other relevant measurements. Those data are recommended to be of high-quality, accurate, align with protocol specifications, and meet regulatory standards. It should exhibit an acceptable level of variation that doesn’t impact study conclusions during statistical analysis. Adherence to protocol requirements is crucial to ensuring the reliability and integrity of the data throughout the trial.

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Navigating the Regulatory Landscape in Nepal's Clinical Research

  • October 31, 2023

Navigating the Regulatory Landscape in Nepal’s Clinical Research: A Comprehensive Guide

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